The Development of Peripheral Nerve Repair Models
Nerve damage refers to injury or impairment to the nervous system. This can lead to loss of sensation, pain, or total paralysis. Nerve repair...
Inflammatory Biomarker Detection Increases Value in Early Drug Development
Inflammation is a key pathological driver in many neurological diseases. The interplay between the central and peripheral nervous systems and the...
Preclinical Efficacy Models of Chemotherapy-Induced Peripheral Neuropathy
Chemotherapeutics agents are commonly used to treat cancer, but come with side effects such as neurotoxicity and peripheral neuropathy, which...
Promoting Diversity for Translational Success
In preclinical efficacy studies, several factors are often overlooked, and it is important to evaluate variables like sex, age, species,...
In Vitro Modeling
The goal of the preclinical development process is to help predict clinical efficacy, emphasizing the importance of studying diseases through models...
The HTX-011 Story
HTX-011 Breakthrough in Pain Management ZYNRELEF, the commercial name for HTX-011, is the first and only FDA-approved extended-release dual-acting...
Wound Healing Models in Pigs
It is important to bridge the gap between lab findings and clinical applications using translational models, ensuring effective translation for human...