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Neural Connections Blog

MD Biosciences insights discussing preclinical research in Pain and Neurodegenerative Conditions

Electrophysiology

The Critical Role of Clinical Relevance in Effective Study Design

Enhancing clinical relevance in early-stage studies can improve efficiency, reduce costs, and guide critical decisions, ultimately advancing more CNS...

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The Development of Peripheral Nerve Repair Models

Nerve damage refers to injury or impairment to the nervous system. This can lead to loss of sensation, pain, or total paralysis. Nerve repair...

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correlation of P25 and vocalization

New Publication - A novel sensory wave (p25) in MOG-EAE model

MD Biosciences has published a new article in the Journal of Pain describing a novel sensory wave (P25) in the MOG-induced EAE model. This article...

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MOG-induced EAE preclinical CRO for neurodegenerative and CNS

Do clinical scores tell us all we need to know?

Multiple sclerosis is a disease in which the immune system attacks the myelin sheath that covers nerve fibers. People suffering from this autoimmune...

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in vivo electrophysiology

What electrophysiology brings to preclinical studies

Neurons communicate with each other as well as other muscles and organs through electrical events called action potentials and neurochemical...

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Monitoring pain in EAE animals experiencing paralysis

Many neurodegenerative diseases such as Multiple Sclerosis, ALS, and Rhett Syndrome involve paralysis. When developing new treatments, it is...

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