Animal Welfare in Preclinical Studies
Maintaining high standards of animal welfare in preclinical research is crucial for both ethical integrity and scientific reliability. Proper pig...
in vivo pain models
Acute Kidney Injury: Insights From In Vivo Biomarker Assessments
In vivo Acute Kidney Injury (AKI) models are commonly used to study renal damage and evaluate potential therapeutic interventions. Several models...
Behavioral Assessments in Preclinical Pain Models
Chronic pain affects 1 in 5 adults in the US, making it one of the most common chronic conditions 1. Approved analgesics often lack efficacy and have...
New Developments: Innovative Cold Pain Testing Methods
Cold testing in rats serves as a crucial tool in pain research, particularly in studying neuropathic pain and assessing the effectiveness of drugs....
Models of Acute Inflammatory Pain
Acute inflammatory pain is commonly associated with tissue injury and is characterized by neuronal plasticity involving both central and peripheral...
Advancing Parkinson’s Research: Insights from Diverse Disease Models
Parkinson’s Disease (PD) is a progressive neurodegenerative movement disorder that affects millions of people worldwide. PD is characterized by the...
The Development of Peripheral Nerve Repair Models
Nerve damage refers to injury or impairment to the nervous system. This can lead to loss of sensation, pain, or total paralysis. Nerve repair...
Preclinical Efficacy Models of Chemotherapy-Induced Peripheral Neuropathy
Chemotherapeutics agents are commonly used to treat cancer, but come with side effects such as neurotoxicity and peripheral neuropathy, which...
Translating Preclinical Data to the Clinic
It's a question that comes up regularly, from scientists who contact us to publications to conference lectures. One of the challenges in preclinical...