Behavioral Assessments in Preclinical Pain Models
Chronic pain affects 1 in 5 adults in the US, making it one of the most common chronic conditions 1. Approved analgesics often lack efficacy and have...
neuropathic pain
The Critical Role of Clinical Relevance in Effective Study Design
Enhancing clinical relevance in early-stage studies can improve efficiency, reduce costs, and guide critical decisions, ultimately advancing more CNS...
New Developments: Innovative Cold Pain Testing Methods
Cold testing in rats serves as a crucial tool in pain research, particularly in studying neuropathic pain and assessing the effectiveness of drugs....
Preclinical Efficacy Models of Chemotherapy-Induced Peripheral Neuropathy
Chemotherapeutics agents are commonly used to treat cancer, but come with side effects such as neurotoxicity and peripheral neuropathy, which...
Advancing Nerve Injury and Repair Models
Understanding Mechanisms Underlying Neuropathic Pain
MDB Neuropathic Pain Porcine Model Publication Featured in Neurobiology of Pain Journal
MDB Scientists recently published a paper titled “Human-like cutaneous neuropathologies associated with a porcine model of peripheral neuritis: a...
Pain Response in Pigs Mimics Human Pain Behavior
The pig peripheral neuritis trauma (PNT) model is an important transitional model that bridges the gap between animal research and the clinic. While...