New Developments: Innovative Cold Pain Testing Methods
Cold testing in rats serves as a crucial tool in pain research, particularly in studying neuropathic pain and assessing the effectiveness of drugs....
Pain
Models of Acute Inflammatory Pain
Acute inflammatory pain is commonly associated with tissue injury and is characterized by neuronal plasticity involving both central and peripheral...
The Development of Peripheral Nerve Repair Models
Nerve damage refers to injury or impairment to the nervous system. This can lead to loss of sensation, pain, or total paralysis. Nerve repair...
The HTX-011 Story
HTX-011 Breakthrough in Pain Management ZYNRELEF, the commercial name for HTX-011, is the first and only FDA-approved extended-release dual-acting...
Porcine Translational Research
Advancing Beyond Rodent and Non-Human Primate Models While rodent models have contributed significantly to our understanding of various diseases and...
Three ways to approach translation
As the general population continues to age, the economic burden of chronic pain and neurodegenerative diseases is increasing and becoming...
The effect of the housing environment and handling on behavior assays
An excerpt from MD Biosciences publication in the Autumn 2022 issue of Göttingen Minipigs Magazine. MD Biosciences operates a neuroscience research...
Preclinical Human Pain Models. Translating to Clinic
Management of acute pain related to surgical intervention, termed postoperative pain, continues to be a major problem facing physicians and patients...
A minipig Model of Incisional pain
The use of animal models for the research of post-operative pain (POP) has been well described[1]. Most POP studies that have been performed to date...