Behavioral Assessments in Preclinical Pain Models
Chronic pain affects 1 in 5 adults in the US, making it one of the most common chronic conditions 1. Approved analgesics often lack efficacy and have...
Pain
New Developments: Innovative Cold Pain Testing Methods
Cold testing in rats serves as a crucial tool in pain research, particularly in studying neuropathic pain and assessing the effectiveness of drugs....
Models of Acute Inflammatory Pain
Acute inflammatory pain is commonly associated with tissue injury and is characterized by neuronal plasticity involving both central and peripheral...
The Development of Peripheral Nerve Repair Models
Nerve damage refers to injury or impairment to the nervous system. This can lead to loss of sensation, pain, or total paralysis. Nerve repair...
The HTX-011 Story
HTX-011 Breakthrough in Pain Management ZYNRELEF, the commercial name for HTX-011, is the first and only FDA-approved extended-release dual-acting...
Porcine Translational Research
Advancing Beyond Rodent and Non-Human Primate Models While rodent models have contributed significantly to our understanding of various diseases and...
Three ways to approach translation
As the general population continues to age, the economic burden of chronic pain and neurodegenerative diseases is increasing and becoming...
The effect of the housing environment and handling on behavior assays
An excerpt from MD Biosciences publication in the Autumn 2022 issue of Göttingen Minipigs Magazine. MD Biosciences operates a neuroscience research...
Preclinical Human Pain Models. Translating to Clinic
Management of acute pain related to surgical intervention, termed postoperative pain, continues to be a major problem facing physicians and patients...