Importance of Diversity in Preclinical Stroke Models
The Need for Diversity in Animal Models The clinical population is diverse, including both sexes, older individuals, and those with comorbid...
preclinical research
Inflammatory Pain Models in Preclinical Research
Arthritic joint pain is a hallmark of inflammatory diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Preclinical models are...
The Critical Role of Clinical Relevance in Effective Study Design
Enhancing clinical relevance in early-stage studies can improve efficiency, reduce costs, and guide critical decisions, ultimately advancing more CNS...
New Developments: Innovative Cold Pain Testing Methods
Cold testing in rats serves as a crucial tool in pain research, particularly in studying neuropathic pain and assessing the effectiveness of drugs....
Promoting Diversity for Translational Success
In preclinical efficacy studies, several factors are often overlooked, and it is important to evaluate variables like sex, age, species,...
In Vitro Modeling
The goal of the preclinical development process is to help predict clinical efficacy, emphasizing the importance of studying diseases through models...
Behavioral Research Assessments & Applications: Quantify Cognitive, Emotional, Sensory & Motor Functions
Neurological diseases often result in a combination of motor and cognitive deficits. Thus, behavioral assessments in conjunction with physiological...