Animal Welfare in Preclinical Studies
Maintaining high standards of animal welfare in preclinical research is crucial for both ethical integrity and scientific reliability. Proper pig...
translational
Acute Kidney Injury: Insights From In Vivo Biomarker Assessments
In vivo Acute Kidney Injury (AKI) models are commonly used to study renal damage and evaluate potential therapeutic interventions. Several models...
The Critical Role of Clinical Relevance in Effective Study Design
Enhancing clinical relevance in early-stage studies can improve efficiency, reduce costs, and guide critical decisions, ultimately advancing more CNS...
Models of Acute Inflammatory Pain
Acute inflammatory pain is commonly associated with tissue injury and is characterized by neuronal plasticity involving both central and peripheral...
Advancing Parkinson’s Research: Insights from Diverse Disease Models
Parkinson’s Disease (PD) is a progressive neurodegenerative movement disorder that affects millions of people worldwide. PD is characterized by the...
electrophysiology: an in vivo biomarker for neurology models
Animal models are commonly used in preclinical development to mimic human disease and response. Over the past several decades, drug developers have...
A minipig Model of Incisional pain
The use of animal models for the research of post-operative pain (POP) has been well described[1]. Most POP studies that have been performed to date...
Why are potential pain therapies getting lost in translation?
It is estimated that 1.5 billion people worldwide suffer from Chronic pain. While research has seen tremendous advances in our understanding of pain...