Advancing Parkinson’s Research: Insights from Diverse Disease Models
Parkinson’s Disease (PD) is a progressive neurodegenerative movement disorder that affects millions of people worldwide. PD is characterized by the...
translational research (2)
Inflammatory Biomarker Detection Increases Value in Early Drug Development
Inflammation is a key pathological driver in many neurological diseases. The interplay between the central and peripheral nervous systems and the...
Preclinical Efficacy Models of Chemotherapy-Induced Peripheral Neuropathy
Chemotherapeutics agents are commonly used to treat cancer, but come with side effects such as neurotoxicity and peripheral neuropathy, which...
Promoting Diversity for Translational Success
In preclinical efficacy studies, several factors are often overlooked, and it is important to evaluate variables like sex, age, species,...
The HTX-011 Story
HTX-011 Breakthrough in Pain Management ZYNRELEF, the commercial name for HTX-011, is the first and only FDA-approved extended-release dual-acting...
Wound Healing Models in Pigs
It is important to bridge the gap between lab findings and clinical applications using translational models, ensuring effective translation for human...
Advancing Nerve Injury and Repair Models
Understanding Mechanisms Underlying Neuropathic Pain
Three ways to approach translation
As the general population continues to age, the economic burden of chronic pain and neurodegenerative diseases is increasing and becoming...