Cell-Based Assays

The neurodegeneration screening assay utilizes primary neurons from rodents, ideal for identifying mode of action and screening compounds before in vivo efficacy studies. We offer in vitro assays for Parkinson's disease, Alzheimer's disease, chemotherapy-induced neuropathic pain, and diabetes. After the conditioning phase, cultures are treated with test compounds and evaluated for their neurodegeneration index.

The neurite outgrowth assay examines the effect of drug candidates on neuronal activity and development. Primary cultures of the nervous system are treated with test compounds to assess their impact on neurite outgrowth or inhibition, which is measured by changes in length and area.