MD Biosciences specializes in cell-based assays utilizing neural tissues derived from animals, neuronal cells, and neural micro-tissues that closely replicate human brain functions. These advanced assays provide a cost-effective and time-efficient solution for compound screening and assessing critical endpoints, such as neuroprotection and synaptogenesis.
Cell-based Assays:
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Neurodegeneration Screening Assay
The neurodegeneration screening assay utilizes primary neurons from rodents and is ideal for identifying mode of action and screening compounds prior to in vivo efficacy studies. After the conditioning phase, cultures are treated with test compounds and evaluated for their neurodegeneration index.
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Synaptic Imaging Assays
The synaptic imaging assay is a powerful model for evaluating the effects of treatments on synapse formation and identification. Key readouts include the ratio of inhibitory and excitatory synapses and synaptic strength.
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Neurite Outgrowth
The neurite outgrowth assay examines the effects of drug candidates on neuronal activity and development. Primary cultures of the nervous system are treated with test compounds to assess their impact on neurite outgrowth or inhibition, which is measured by changes in length and area.
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At MD Biosciences, we’re not just a service provider—we’re your dedicated partner in drug development. With industry-leading expertise, we offer tailored study designs, translational models, and comprehensive endpoint assessments. Our commitment to short lead times and competitive pricing, combined with our deep scientific knowledge, ensures your research progresses efficiently and effectively. Collaborate with us to turn your scientific vision into reality.