Cell-based Assays
Efficacy Models
PK/PD & Toxicology
Pain
Neurodegeneration
Neuroinflammation
Wound Healing
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Carrageenan-Induced Inflammatory Pain
Acute inflammatory pain is commonly associated with tissue injury and manifests itself as an expression of neuronal plasticity consisting of central and peripheral sensitization. Tissue injury causes a release of inflammatory mediators from damaged cells, which become central to the initiation of an inflammatory cascade.