The Pig as a translational model for wound healing
MD Biosciences provides advanced wound healing models in both rodents and pigs. Rodent models are ideal for early-stage research, while our pig models are best suited for assessing wound healing efficacy and conducting IND-enabling studies due to their physiological similarities to humans. Like humans, pigs heal partial-thickness wounds primarily through re-epithelialization rather than wound contraction. For studies focused on comorbidities, our models also feature aged and diabetic animals, offering a comprehensive platform to evaluate therapeutic interventions. Additional readouts, such as biomarker analysis and histology are available and integrated into our studies. Explore how our tailored models can advance your wound healing studies.
Wound Healing Models:
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Incisional Wound Models
Species available: mouse, rat, pig
Study Duration: 14-30 days
Standard assessments: body weight, clinical signs, wound score, digital images, gross pathology, histology
Optional assessments: open field for locomotor activity, von Frey pain assessment, PK, IHC, biomarker
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Excisional Wound Model
Species available: mouse, rat, pig
Study Duration: 14-30 days
Standard assessments: body weight, clinical signs, wound score, digital images, gross pathology, histology
Optional assessments: open field for locomotor activity, von Frey pain assessment, PK, IHC, biomarker
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Burn Wound Models
Species available: mouse, rat, pig
Study Duration: 14-30 days
Standard assessments: body weight, clinical signs, wound score, digital images, gross pathology, histology
Optional assessments: open field for locomotor activity, von Frey pain assessment, PK, IHC, biomarker
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Diabetic Wound Model
Species available: mouse, rat
Study Duration: 14-30 days
Standard assessments: body weight, clinical signs, wound score, digital images, gross pathology, histology
Optional assessments: open field for locomotor activity, von Frey pain assessment, PK, IHC, biomarker
Scientific Data
Figure 2. Wound area reduction (% relative to incision day (Day 0). Animals were examined on study days 1, 3, 7, 10 and 14. The closure of the incision was monitored, and wound area was compared to baseline at each time point
Wound Healing Datasheet
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At MD Biosciences, we’re not just a service provider—we’re your dedicated partner in drug development. With industry-leading expertise, we offer tailored study designs, translational models, and comprehensive endpoint assessments. Our commitment to short lead times and competitive pricing, combined with our deep scientific knowledge, ensures your research progresses efficiently and effectively. Collaborate with us to turn your scientific vision into reality.