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EAE Multiple Sclerosis

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Advancing Preclinical Research with EAE Models

MD Biosciences provides a comprehensive suite of well-characterized Experimental Autoimmune Encephalomyelitis (EAE) rodent models to advance inflammation and multiple sclerosis research. Our MOG, PLP, and MBP EAE models deliver actionable insights for therapeutic development, supported by advanced assessments that enhance translational relevance.

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Scientific Data

Electrophysiology in EAE

The figure shows motor evoked potentials in naïve, mild, and severe EAE models. Electrophysiological characterization shows how early EAE causes desynchronized neural activity and hypersensitivity, leading to motor and sensory loss in later stages.

 

Assessments

MD Biosciences offers comprehensive in vivo measures and endpoint assessments, delivering robust data packages to support critical research decisions in the evolving landscape of drug development and biomedical research.

behavior

Behavior 

Conduct extensive pain, sensory, motor, and cognitive behavioral testing.

biomarker

Biomarkers

Explore inflammatory and pain biomarkers in disease-specific tissues.

histology

Histology

Characterize tissue and cellular changes in disease, pain, and neurodegeneration.

electrophysiology

Electrophysiology

Measure motor and sensory evoked potentials to assess disease progression and pain.

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MD Biosciences is your dedicated partner in drug development, offering tailored study designs, translational models, and comprehensive endpoint assessments. With short lead times, competitive pricing, and deep scientific expertise, we help move your pipeline forward efficiently.

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