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Parkinson's Disease

Unique approaches to modeling Parkinson's disease in preclinical models. 

 

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At MD Biosciences, we provide cutting-edge Parkinson's disease research through a diverse range of animal models. Our offerings include the traditional neurotoxin models, such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 6-hydroxydopamine (6-OHDA), along with advanced genetic models. These models are designed to support translational studies with precise assessments and targeted endpoints, ensuring that your research advances effectively toward therapeutic breakthroughs.

 

Parkinson's Disease Models:

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Scientific Data

HC staining with Tyrosine Hydroxylase (TH) antibody. 

Figure A. Subgross image of Substantia Nigra sections showing reduction in number of TH-positive cells in the right hemisphere vs. the left intact hemisphere. Figure B. High magnification of TH-positive dopaminergic neurons. Figure C. Subgross image of TH-positive nerve fibers in section of striatum of the Left intact hemisphere contrasted to the lack of TH staining in the right hemisphere injected with 6-OHDA.  

STAINING-6OHDA-SUBSTANTIA-NIGRA-MDBIOSCIENCES
 

PD datasheet

 

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At MD Biosciences, we’re not just a service provider—we’re your dedicated partner in drug development. With industry-leading expertise, we offer tailored study designs, translational models, and comprehensive endpoint assessments. Our commitment to short lead times and competitive pricing, combined with our deep scientific knowledge, ensures your research progresses efficiently and effectively. Collaborate with us to turn your scientific vision into reality.

 

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