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Preclinical Models of Pain

A preclinical partner focused on understanding the neural pathways of pain and the mechanisms involved.

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Pain Expertise

MD Biosciences is dedicated to advancing the study of pain and neurodegenerative diseases. Understanding pain and novel mechanisms requires deep scientific knowledge as well as the expertise and infrastructure to effectively evaluate therapeutic candidates in early and translational phases. As with any model, selecting the right species, stimuli, assessments, and endpoints is critical to conducting quality studies that provide meaningful insight into the condition and potential therapies. MD Biosciences’ expertise in study design ensures the generation of predictive data from preclinical research.

Assessments

MD Biosciences offers comprehensive in vivo measures and endpoint assessments, delivering robust data packages to support critical research decisions in the evolving landscape of drug development and biomedical research.
behavior

Behavior 

Conduct extensive pain, sensory, motor, and cognitive behavioral testing.

biomarker

Biomarkers

Explore inflammatory and pain biomarkers from disease-specific tissues.

histology

Histology

Analyze tissue and cellular changes in disease, pain, and neurodegeneration.

electrophysiology

Electrophysiology

Measure motor and sensory evoked potentials to assess disease progression and pain.

Understanding behavior as a result of pain.

Measuring pain is often times straight forward using stimuli and measuring the resulting response. But the clinical situation not only evaluates response to the stimuli but the emotional component that patients report. In animal studies, we must rely on vocalization assessments and tests such as the open field to see how animals exhibit anxiety and behave emotionally as a result of the painful condition. 

open field_POP publication

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READY TO DISCUSS YOUR PROGRAM?

MD Biosciences is your dedicated partner in drug development, offering tailored study designs, translational models, and comprehensive endpoints. With short lead times, competitive pricing, and deep scientific expertise, we help move your pipeline forward efficiently.

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