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Preclinical Models of Pain

A preclinical partner focused on understanding the neural pathways of pain and the mechanisms involved.

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mdbiosciences-neurology-leading-preclinical-CRO-1

Pain Expertise

MD Biosciences is dedicated to the study of pain and neurodegenerative diseases. The understanding of pain and novel mechanisms requires a deep understanding of the science as well as the resources in terms of expertise and infrastructure to effectively study therapeutic candidates in early and translational phases. 

As with any model, the right selection of species, stimuli, assessments, and end-point analysis leads to a quality study that brings insight into the condition and potential therapeutic. MD Biosciences expertise in study design contributes to predictive data from preclinical studies. 

Assessments

MD Biosciences offers comprehensive in vivo measures and endpoint assessments, delivering robust data packages to support critical research decisions in the evolving landscape of drug development and biomedical research.
behavior

Behavior 

Conduct extensive pain, sensory, motor, and cognitive behavioral testing.

biomarker

Biomarkers

Explore inflammatory and pain biomarkers from disease-specific tissues.

histology

Histology

Analyze tissue and cellular changes in disease, pain, and neurodegeneration.

electrophysiology

Electrophysiology

Measure motor and sensory evoked potentials to assess disease progression and pain.

Understanding behavior as a result of pain.

Measuring pain is often times straight forward using stimuli and measuring the resulting response. But the clinical situation not only evaluates response to the stimuli but the emotional component that patients report. In animal studies, we must rely on vocalization assessments and tests such as the open field to see how animals exhibit anxiety and behave emotionally as a result of the painful condition. 

open field_POP publication
 

Preclinical Pain Models

READY TO DISCUSS YOUR PROGRAM?

MD Biosciences is your dedicated partner in drug development, offering tailored study designs, translational models, and comprehensive endpoints. With short lead times, competitive pricing, and deep scientific expertise, we help move your pipeline forward efficiently.

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