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Acute Inflammatory Pain

The CFA-induced and Carrageenan-induced inflammatory pain models.

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Pain Associated with Tissue Injury

MD Biosciences offers acute inflammatory pain models that can be extended to evaluate a more chronic inflammatory pain state. In models like CFA or carrageenan, we can measure the release of cytokines and their role in the initiation and maintenance of the inflammatory response.
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Scientific Data

Biomarker Analysis in the CFA Model

Biomarker analysis provides precise insights into pro- and anti-inflammatory cytokines in paw skin, CSF, and plasma, uncovering both local and systemic drug effects. The graphs illustrate a significant reduction in pro- and anti-inflammatory cytokines within the CFA rat model, indicating a reduction in the pro-inflammatory response.

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Assessments

MD Biosciences offers comprehensive in vivo measures and endpoint assessments, delivering robust data packages to support critical research decisions in the evolving landscape of drug development and biomedical research.
behavior

Behavior 

Conduct extensive pain, sensory, motor, and cognitive behavioral testing.

biomarker

Biomarkers

Explore inflammatory and pain biomarkers in disease-specific tissues.

histology

Histology

Characterize tissue and cellular changes in disease, pain, and neurodegeneration.

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READY TO DISCUSS YOUR PROGRAM?

MD Biosciences is your dedicated partner in drug development, offering tailored study designs, translational models, and comprehensive endpoints. With short lead times, competitive pricing, and deep scientific expertise, we help move your pipeline forward efficiently.

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