<img height="1" width="1" style="display:none;" alt="" src="https://px.ads.linkedin.com/collect/?pid=3993628&amp;fmt=gif">
Skip to the main content.
Request Proposal
Request Proposal

Peripheral Nerve Repair

SPEAK WITH A SCIENTIST

mdbiosciences-neurology-leading-preclinical-CRO-1

Advancing Preclinical Research with Peripheral Nerve Repair Models

 MD Biosciences offers specialized rodent and translational pig models to advance nerve repair research. Pigs are a promising model for peripheral nerve repair studies due to their ability to mimic critical gaps and facilitate various functional assays, such as computerized gait analysis, compound motor action potential (cMAP) tests, and distal sensory nerve action potential (DSNAP) assessments. Our sciatic nerve dissection model mimics peripheral nerve damage, providing a robust platform to evaluate nerve repair technologies, including wraps, conduits, and fillers.

Our state-of-the-art facilities and expert team provide a multifaceted approach with clinically relevant assessments, including histology, immunohistochemistry (IHC), biomarker analysis, behavioral assessments, and in vivo electrophysiology.
Speak with a scientist
Scientific Data

Catwalk Analysis in Pig Tibial Nerve Repair Model

The figure shows the maximum vertical force exerted by pigs on each leg after peroneal dissection. A force ratio greater than 1 indicates greater force on the intact leg, with recovery observed six weeks post-implantation in tube-implanted pigs.

 
Peripheral Nerve Repair_Pig

Assessments

MD Biosciences offers comprehensive in vivo measures and endpoint assessments, delivering robust data packages to support critical research decisions in the evolving landscape of drug development and biomedical research.
behavior

Behavior 

Conduct extensive pain, sensory, motor, and cognitive behavioral testing.

biomarker

Biomarkers

Explore inflammatory and pain biomarkers in disease-specific tissues.

histology

Histology

Characterize tissue and cellular changes in disease, pain, and neurodegeneration.

electrophysiology

Electrophysiology

Measure motor and sensory evoked potentials to assess disease progression and pain.

READY TO DISCUSS YOUR PROGRAM?

MD Biosciences is your dedicated partner in drug development, offering tailored study designs, translational models, and comprehensive endpoints. With short lead times, competitive pricing, and deep scientific expertise, we help move your pipeline forward efficiently.

Request Proposal