Wound Healing

The incisional wound model is designed to study surgical wound healing and tissue repair in both pigs and rodents. This model involves creating a full-thickness incision through the skin and fascia, with the option of muscle retraction to replicate operational wounds. It is commonly used to evaluate the effects of treatments on incision closure and post-surgical pain. Additionally, it is ideal for testing new incision-washing fluids on unsutured wounds, as well as advancements in sutures, pain relievers, and adhesives.

The excisional wound model is used to study tissue regeneration and wound closure in both pigs and rodents. This model involves creating a full-thickness wound by removing all layers of skin and fascia. It is commonly used to evaluate therapies aimed at improving local wound healing, such as a bandage, sponge, biologic, or other intervention.

The burn wound model is used to study thermal injuries and burn healing in both pigs and rodents. This model involves applying controlled heat to create a burn injury. It is utilized to evaluate interventions for burn recovery, including reducing inflammation, promoting tissue regeneration, supporting blood vessel formation, and encouraging nerve-ending growth. Additionally, it is valuable for assessing the effectiveness of new technologies, such as creams, liquids, and other innovations.

The diabetic wound model is used to study impaired healing under diabetic conditions in both pigs and rodents. This model involves creating wounds in a diabetic animal to evaluate treatments aimed at targeting chronic wound healing and addressing complications associated with diabetes.