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Arthritic Inflammatory Pain

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Advancing Preclinical Research with Inflammatory Pain Models

At MD Biosciences, we offer the monosodium iodoacetate (MIA) model for osteoarthritis pain, and the collagen-induced arthritis (CIA) model for rheumatoid arthritis pain. These models include both inflammatory and neuropathic pain components. We provide models in rats and joint inflammation models in pigs, enabling comprehensive studies of pain mechanisms. 
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MIA rats
Scientific Data

Von Frey in MIA Rodent Model

Response to von Frey in the rat MIA-induced OA model shows that the positive controls have an increased withdrawal force 14 days after treatment. 

EXPLORE RESOURCES

Assessments

MD Biosciences offers comprehensive in vivo measures and endpoint assessments, delivering robust data packages to support critical research decisions in the evolving landscape of drug development and biomedical research.
behavior

Behavior 

Conduct extensive pain, sensory, motor, and cognitive behavioral testing.

biomarker

Biomarkers

Explore inflammatory and pain biomarkers in disease-specific tissues.

histology

Histology

Characterize tissue and cellular changes in disease, pain, and neurodegeneration.

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READY TO DISCUSS YOUR PROGRAM?

MD Biosciences is your dedicated partner in drug development, offering tailored study designs, translational models, and comprehensive endpoints. With short lead times, competitive pricing, and deep scientific expertise, we help move your pipeline forward efficiently.

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